plague
noun
a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal
any epidemic disease with a high death rate
a swarm of insects that attack plants
“a plague of grasshoppers”
Synonymsinfestationany large scale calamity (especially when thought to be sent by God)
an annoyance
“those children are a damn plague”
verb
cause to suffer a blight
“Too much rain may blight the garden with mold”
Synonymsblightannoy continually or chronically
“He is known to harry his staff when he is overworked”
“This man harasses his female co-workers”
Source: WordNet 3.1, Princeton University
